Atrial Fibrillation, Familial, 11; Atfb11

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

Atrial fibrillation is the most common sustained cardiac rhythm disturbance, affecting more than 2 million Americans, with an overall prevalence of 0.89%. The prevalence increases rapidly with age, to 2.3% between the ages of 40 and 60 years, and to 5.9% over the age of 65. The most dreaded complication is thromboembolic stroke (Brugada et al., 1997).For a discussion of genetic heterogeneity of familial atrial fibrillation, see ATFB1 (OMIM ).

Genes related to Atrial Fibrillation, Familial, 11; Atfb11

GJA5

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Clinical Features

Phenotypes and symptoms related to Atrial Fibrillation, Familial, 11; Atfb11

Stroke
Atrial fibrillation
Thromboembolic stroke

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Atrial Fibrillation, Familial, 11; Atfb11 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Atrial Fibrillation Panel. By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States). SCN1B, SCN2B, SCN5A, SCN3B, GJA5, ABCC9, KCNA5, KCND3, KCNE1, KCNE2, KCNH2, KCNJ2, KCNQ1, LMNA, NPPA, NUP155 Specificity 7 % Genes 100 %
GJA5. By Institute for Human Genetics University Clinic Freiburg (Germany). GJA5 Specificity 100 % Genes 100 %
Cardiac Arrhythmia NGS Multi-Gene Panel (48 genes), Sequence & CNV analysis. By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam (Netherlands). RYR2, SCN10A, SCN1B, SCN2B, SCN4B, SCN5A, SNTA1, TNNT2, TRDN, CACNA1C, CACNA1D, CACNA2D1, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV3, SLMAP, HCN4 , (...) View the complete list with 27 more genes Panel complete gene list RYR2, SCN10A, SCN1B, SCN2B, SCN4B, SCN5A, SNTA1, TNNT2, TRDN, CACNA1C, CACNA1D, CACNA2D1, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV3, SLMAP, HCN4, RANGRF, TRPM4, SCN3B, GPD1L, DPP6, AKAP9, GJA5, ANK2, ABCC9, KCNA5, KCND3, KCNE1, KCNE5, KCNE2, KCNE3, KCNH2, KCNJ2, KCNJ5, KCNJ8, KCNQ1, LAMP2, LMNA, ASPH, NPPA, PKP2, PLN, PRKAG2 Specificity 3 % Genes 100 %
Atrial fibrillation, familial 11 (sequence analysis of GJA5 gene). By CGC Genetics (Portugal). GJA5 Specificity 100 % Genes 100 %
Familial Atrial Fibrillation Syndrome Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). SCN1B, SCN2B, SCN5A, SCN3B, GJA5, ABCC9, KCNA5, KCND3, KCNE1, KCNE5, KCNE2, KCNH2, KCNJ2, KCNQ1, NPPA Specificity 7 % Genes 100 %
Atrial Fibrillation via GJA5 Gene Sequencing with CNV Detection. By PreventionGenetics PreventionGenetics (United States). GJA5 Specificity 100 % Genes 100 %
Comprehensive Cardiology Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). RYR1, RYR2, SCN1B, SCN2B, SCN4B, SCN5A, SCO2, SGCD, SGCG, BRAF, SLC25A4, SNTA1, SOS1, SREBF2, TAZ, TBX3, TBX5, TCAP, TGFB2, TGFB3 , (...) View the complete list with 143 more genes Panel complete gene list RYR1, RYR2, SCN1B, SCN2B, SCN4B, SCN5A, SCO2, SGCD, SGCG, BRAF, SLC25A4, SNTA1, SOS1, SREBF2, TAZ, TBX3, TBX5, TCAP, TGFB2, TGFB3, TGFBR2, KLF10, TMPO, TNNC1, TNNI3, TNNT2, TPM1, TRDN, TTN, TTR, VCL, ZIC3, ACTA1, ZBTB17, ACTA2, MYOZ2, SLC2A10, ABCG5, ABCG8, CACNA1C, CACNA2D1, PRDM16, CACNB2, LMF1, JPH2, ACTC1, CALM1, CRELD1, CASQ2, CAV3, CBL, SHOC2, CBS, LDB3, ANKRD1, SALL4, ZHX3, SELENON, TRIM63, MYLK2, ACTN2, HCN4, APOA5, RANGRF, TRPM4, FKRP, LDLRAP1, CETP, CREB3L3, CALR3, SCN3B, PDLIM3, MIB1, COL3A1, COL5A2, COX15, MYPN, DOLK, CRYAB, CSRP3, NKX2-5, GPIHBP1, RBM20, DES, TMEM43, GPD1L, DMD, NEXN, GATAD1, DPP6, HSPB8, DSC2, DSG2, DSP, DNAJC19, DTNA, EFEMP2, ELN, EMD, CAVIN4, EYA4, FBN1, FBN2, FKTN, FHL1, FHL2, AKAP9, GAA, GCKR, GJA5, ALMS1, GLA, HADHA, HFE, ANK2, HRAS, ABCC9, APOA4, ILK, APOC2, APOE, JAG1, JUP, KCNA5, KCND3, KCNE1, KCNE2, KCNE3, KCNH2, KCNJ2, KCNJ5, KCNJ8, KCNQ1, KRAS, LAMA2, LAMA4, LAMP2, LDLR, LMNA, LTBP2, SMAD3, SMAD4, MAP2K1, MAP2K2, MYBPC3, MYH11, MYH6, MYH7, MYL2, MYL3, MYLK, MYO6, NODAL, NOTCH1, NPPA, NRAS, PKP2, PLN, PRKAG2, PRKAR1A, BAG3, PTPN11, RAF1 Specificity 1 % Genes 100 %
Comprehensive Cardiac Arrhythmia Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). RYR2, SCN10A, SCN1B, SCN2B, SCN4B, SCN5A, SNTA1, TGFB3, TNNI3, TRDN, CACNA1C, CACNA2D1, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV3, LDB3, SLMAP , (...) View the complete list with 35 more genes Panel complete gene list RYR2, SCN10A, SCN1B, SCN2B, SCN4B, SCN5A, SNTA1, TGFB3, TNNI3, TRDN, CACNA1C, CACNA2D1, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV3, LDB3, SLMAP, HCN4, RANGRF, TRPM4, TNNI3K, SCN3B, NKX2-5, DES, TMEM43, GPD1L, DSC2, DSG2, DSP, AKAP9, GJA5, ANK2, ABCC9, JUP, KCNA5, KCND3, KCNE1, KCNE5, KCNE2, KCNE3, KCNH2, KCNJ2, KCNJ5, KCNJ8, KCNK3, KCNQ1, MYH6, MYL4, NPPA, PKP2, PLN, PRKAG2 Specificity 2 % Genes 100 %

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Sources and references

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