Fanconi Anemia, Complementation Group T; Fanct

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

Fanconi anemia is characterized by genomic instability, increased susceptibility to cancer development, and bone marrow failure associated with various developmental abnormalities, such as radial ray anomalies or short stature (summary by Hira et al., 2015).For a discussion of genetic heterogeneity of Fanconi anemia, see FANCA (OMIM ).

Genes related to Fanconi Anemia, Complementation Group T; Fanct

UBE2T

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Clinical Features

Top most frequent phenotypes and symptoms related to Fanconi Anemia, Complementation Group T; Fanct

Short stature
Neoplasm
Anemia
Thrombocytopenia
Polydactyly
Facial palsy
Leukemia
Pancytopenia
Short thumb
Bone marrow hypocellularity

And another 5 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Fanconi Anemia, Complementation Group T; Fanct Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Fanconi Anemia Sequencing Panel. By Genetic Services Laboratory University of Chicago (United States). BRCA2, XRCC2, BRIP1, FANCL, FANCM, SLX4, UBE2T, FANCI, PALB2, ERCC4, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, RAD51C Specificity 6 % Genes 100 %
Hereditary Myeloid Malignancy and Inherited Bone Marrow Failure Panel. By Genetic Services Laboratory University of Chicago (United States). RPL11, RPL15, RPL26, RPL35A, RPL5, RPS10, RPS19, RPS24, RPS26, RPS7, RUNX1, BLM, BRCA1, BRCA2, SRP72, TERC, TERT, TINF2, TP53, WAS , (...) View the complete list with 58 more genes Panel complete gene list RPL11, RPL15, RPL26, RPL35A, RPL5, RPS10, RPS19, RPS24, RPS26, RPS7, RUNX1, BLM, BRCA1, BRCA2, SRP72, TERC, TERT, TINF2, TP53, WAS, IKZF1, SAMD9, SAMD9L, NHP2, NOP10, VPS45, CBL, RTEL1, HAX1, POT1, CEBPA, SBDS, BRIP1, FANCL, SBF2, SLX4, CSF3R, G6PC3, UBE2T, ACD, NAF1, WRAP53, FANCI, CXCR4, USB1, PALB2, CTC1, DNAJC21, DKC1, ANKRD26, ELANE, ERCC4, ETV6, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, ALAS2, GATA1, GATA2, GFI1, MLH1, MPL, MSH2, MSH6, NBN, NF1, ATM, PARN, PAX5, PMS2, PTPN11, RAD51, RAD51C, RBM8A Specificity 2 % Genes 100 %
Fanconi Anemia Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). BRCA1, BRCA2, XRCC2, BRIP1, FANCL, FANCM, SLX4, UBE2T, FANCI, PALB2, ERCC4, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, MAD2L2, RAD51 , (...) View the complete list with 1 more genes Panel complete gene list BRCA1, BRCA2, XRCC2, BRIP1, FANCL, FANCM, SLX4, UBE2T, FANCI, PALB2, ERCC4, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, MAD2L2, RAD51, RAD51C Specificity 5 % Genes 100 %
NGS Panel for Fanconi anemia. By BLOODGENETICS BLOODGENETICS (Spain). BRCA1, BRCA2, XRCC2, BRIP1, FANCL, FANCM, SLX4, UBE2T, RFWD3, FANCI, PALB2, ERCC4, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, MAD2L2 , (...) View the complete list with 2 more genes Panel complete gene list BRCA1, BRCA2, XRCC2, BRIP1, FANCL, FANCM, SLX4, UBE2T, RFWD3, FANCI, PALB2, ERCC4, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, MAD2L2, RAD51, RAD51C Specificity 5 % Genes 100 %
UBE2T. By Fulgent Genetics Fulgent Genetics (United States). UBE2T Specificity 100 % Genes 100 %
FANCONI ANEMIA: NGS PANEL. By Laboratorio de Genetica Clinica SL (Spain). BRCA2, XRCC2, BRIP1, FANCL, FANCM, SLX4, UBE2T, FANCI, PALB2, ERCC4, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, RAD51C Specificity 6 % Genes 100 %
Tempus xT assay. By Tempus Labs, Inc. (United States). BCL6, RIT1, BCL7A, BCR, ROS1, RPL5, RPS15, RPS6KB1, RUNX1, RXRA, BLM, SDHA, SDHB, SDHC, SDHD, SEC23B, SEMA3C, BMPR1A, SF3B1, SRSF2 , (...) View the complete list with 555 more genes Panel complete gene list BCL6, RIT1, BCL7A, BCR, ROS1, RPL5, RPS15, RPS6KB1, RUNX1, RXRA, BLM, SDHA, SDHB, SDHC, SDHD, SEC23B, SEMA3C, BMPR1A, SF3B1, SRSF2, SGK1, SCG5, FOXL2, BRAF, BRCA1, BRCA2, SLIT2, SMARCA1, SMARCA4, SMARCB1, SMARCE1, ARID1A, SMC1A, KDM5C, SMO, SOD2, SOX10, SOX2, SOX9, SPINK1, SPOP, SRC, BTG1, BTK, STAG2, STAT3, STAT4, STAT5A, STAT5B, STAT6, STK11, AURKB, AURKA, BUB1B, SYK, EPCAM, TAF1, TBX3, HNF1A, HNF1B, TCF3, TCF7L2, TCL1A, TERT, TGFBR2, NKX2-1, TMPRSS2, TNF, TNFAIP3, TNFRSF14, TNFRSF17, CD40, FAS, TNFRSF9, CD70, MED12, TOP1, TOP2A, TP53, TPM1, TPMT, TRAF3, EGLN1, TSC1, TSC2, TYMS, U2AF1, UGT1A1, UGT1A9, UMPS, KDM6A, VEGFA, VHL, WEE1, NSD2, WRN, WT1, XPA, XPC, XPO1, XRCC1, XRCC2, XRCC3, ACTA2, ZNF217, KAT6A, IKZF1, BCL11B, BRD4, FBXO11, CTCF, KMT2C, HDAC4, CIC, NSD1, CRLF2, PPP1R15A, NHP2, NOP10, CALR, IKBKE, CASP8, CASR, RUNX1T1, CBFB, CBL, CBLB, CBR3, P2RY8, SETBP1, CCND1, CCND2, KMT2B, CCND3, CCNE1, CBLC, TP63, CD19, CARD11, CD22, SUFU, SLC49A4, KIF1B, FBXW7, CDC73, BCLAF1, HSPH1, FRS2, CD79A, CD79B, PIAS4, RNF139, PALLD, ARHGAP26, DICER1, SUZ12, ACVR1B, POT1, ARID5B, CDH1, SPEN, CD274, CDK4, CDK6, CDK8, CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C, ARID2, ARID1B, EMSY, RSF1, ZNRF3, PHF6, ERRFI1, ASXL1, CEBPA, IFNL3, SETD2, HAVCR2, RNF43, KLHL6, PDCD1LG2, CCDC6, CFTR, CKS1B, CHD2, CHD4, CHEK1, SOCS1, GALNT12, GREM1, SPRED1, AJUBA, BRIP1, DIS3, FANCL, BCOR, FOXQ1, MIB1, QKI, RINT1, PREX2, ZRSR2, NUDT15, FANCM, KEAP1, CREBBP, CRKL, SLX4, CDK12, CSF1R, CSF3R, SMC3, TENT5C, YEATS4, DOT1L, UBE2T, CTLA4, CTNNA1, CTNNB1, CTRC, FANCI, CUX1, CXCR4, BCORL1, ABRAXAS1, CYLD, ZNF750, TET2, CYP1B1, SDHAF2, TMEM127, PALB2, CTC1, CYP2D6, CYP3A5, SLC47A2, DAXX, AMER1, TIGIT, GEN1, DDB2, DDR2, FLCN, DDX3X, TMEM173, RICTOR, DIS3L2, DKC1, TANC1, TBL1XR1, SH2B3, DYNC2H1, DNM2, DNMT3A, PBRM1, VSIR, DPYD, SLC26A3, TUSC3, RPTOR, CEP57, EBF1, EGF, EGFR, ELF3, ENG, EP300, EPHA2, EPHA7, EPHB1, EPHB2, EPOR, ERBB2, ERBB3, ERBB4, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, ERG, ETS1, ETS2, ETV1, ETV4, ETV5, ETV6, EWSR1, EZH2, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FAT1, FCGR2A, FCGR3A, FDPS, FGF1, FGF10, FGF14, FGF2, FGF23, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, FGFR1, FGFR2, FGFR3, FGFR4, FH, FHIT, KLLN, FLG, FLT1, FLT3, FLT4, FNTB, FOXO1, FOXO3, FOXP1, AKT1, AKT2, AKT3, MTOR, ABCB1, FUBP1, G6PD, GATA1, GATA2, GATA3, GATA4, GATA6, ALK, TAP1, GLI1, GNA11, GNA13, GNAQ, GNAS, TAP2, GPC3, GPS2, GRIN2A, ARHGAP35, GRM3, GSTP1, H19, HIST1H1E, H3F3A, HIST1H4E, HAS3, HDAC1, HDAC2, HGF, HIF1A, HLA-A, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DQB2, HLA-DRA, HLA-DRB1, HLA-DRB5, HLA-E, HLA-F, HLA-G, FOXA1, HOXB13, HRAS, HSP90AA1, IDH1, IDH2, ABCC3, IFIT1, IFIT2, IFIT3, IFNAR1, IFNAR2, IFNGR1, IFNGR2, APC, BIRC3, IL10RA, IL15, IL2RA, IL6R, IL7R, IDO1, ING1, INPP4B, IRF1, IRF2, IRF4, IRS2, ITPKB, JAK1, JAK2, JAK3, JUN, KDR, KEL, KIT, KRAS, MAFB, AR, ARAF, LAG3, LDLR, LMNA, LMO1, RHOA, LRP1B, LYN, LZTR1, MAD2L2, SMAD2, SMAD3, SMAD4, MAF, MALT1, MAP2K1, MAP2K2, MAP2K4, MAP3K1, MAP3K7, MAPK1, MAX, MC1R, MCL1, MDM2, MDM4, MEF2B, MEN1, MET, MGMT, CIITA, MITF, MKI67, MLH1, MLH3, KMT2D, MLLT3, MPL, MRE11, MS4A1, MSH2, MSH3, MSH6, MTAP, MTHFR, MTRR, MUTYH, ASNS, MYB, MYC, MYCL, MYCN, MYD88, MYH11, ABL1, NBN, NCOR1, NCOR2, ABL2, NF1, ZFHX3, NF2, NFE2L2, NFKBIA, NOTCH1, NOTCH2, NOTCH3, NPM1, ATIC, ATM, NRAS, NRG1, NT5C2, NTHL1, NTRK1, NTRK2, NTRK3, NUP98, PAK1, PRKN, PAX5, PAX7, PAX8, PCBP1, ATP7B, PDCD1, PDGFRA, PDGFRB, PDK1, PDPK1, ATR, ATRX, PIK3C2B, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PIK3R2, PIM1, AXIN1, AXIN2, AXL, PLCG2, PML, PMS1, PMS2, B2M, PHOX2B, POLD1, POLE, POLH, POU2F2, PPP2R1A, PPP2R2A, PPP6C, PRCC, PRDM1, PRKAR1A, PRSS1, PRSS2, BAP1, BARD1, PTCH1, PTCH2, PTEN, PTPN11, PTPN13, PTPN22, PTPRD, RAC1, RAD21, RAD50, RAD51, RAD51C, RAD51B, RAD51D, RAD54L, RAF1, RANBP2, RARA, RASA1, RB1, KDM5A, BCL10, RBM10, BCL2L1, BCL2L11, RECQL4, RET Specificity 1 % Genes 100 %
Fanconi Anemia: gene sequencing panel. By CEN4GEN Institute for Genomics and Molecular Diagnostics (Canada). BRCA2, XRCC2, BRIP1, FANCL, FANCM, SLX4, UBE2T, RFWD3, FANCI, PALB2, ERCC4, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, MAD2L2, RAD51 , (...) View the complete list with 1 more genes Panel complete gene list BRCA2, XRCC2, BRIP1, FANCL, FANCM, SLX4, UBE2T, RFWD3, FANCI, PALB2, ERCC4, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, MAD2L2, RAD51, RAD51C Specificity 5 % Genes 100 %

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Sources and references

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