Immunoglobulin Kappa Light Chain Deficiency; Igkcd
Description
Deficiencies in immunoglobulin (Ig) isotypes (including: isolated IgG subclass deficiency, IgG sublcass deficiency with IgA deficiency and kappa chain deficiency) are primary immunodeficiencies that are often asymptomatic but can be characterized by recurrent, often pyogenic, sinopulmonary infections.
Genes related to Immunoglobulin Kappa Light Chain Deficiency; Igkcd
- IGHG2
- IGKC
Clinical Features
Phenotypes and symptoms related to Immunoglobulin Kappa Light Chain Deficiency; Igkcd
- Diarrhea
- Recurrent respiratory infections
- Recurrent infections
- Respiratory tract infection
- Abnormal immunoglobulin level
Incidence and onset information
— Not enough data available about incidence and published cases.
Accelerate your rare disease diagnosis with us
Immunoglobulin Kappa Light Chain Deficiency; Igkcd Recommended genes panels
| Panel Name, Specifity and genes Tested/covered |
|---|
|
Antibody deficiencies Panel.
By CeGaT GmbH in Germany.
UNG, RTEL1, BTK, TCF4, DKC1, TNFRSF13B, AICDA, CD40, CD40LG, LRBA, NFKB2, PIK3R1, CD19, CR2, CD81, ICOS, TNFRSF13C, MS4A1, LRRC8A, BLNK , (...)
View the complete list with 8 more genes
Specificity
4 %
Genes
50 % |
Alternate names
Immunoglobulin Kappa Light Chain Deficiency; Igkcd Is also known as kappa chain deficiency;igg subclass deficiency with iga subclass deficiency; isolated igg subclass deficiency; kappa-chain deficiency; selective igg subclass deficiency.
If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like SCLEROSING CHOLANGITIS, NEONATAL; NSC PFEIFFER SYNDROME TYPE 2 CRI-DU-CHAT SYNDROME