Insulinoma
Description
Insulinoma is the most common type of functioning pancreatic neuroendocrine tumor (see this term) characterized most commonly by a solitary, small pancreatic lesion that causes hyperinsulinemic hypoglycemia.
Clinical Features
Top most frequent phenotypes and symptoms related to Insulinoma
- Seizures
- Tremor
- Fatigue
- Behavioral abnormality
- Hyperhidrosis
- Anxiety
- Lethargy
- Paresthesia
- Coma
- Generalized muscle weakness
And another 24 symptoms. If you need more information about this disease we can help you.
Incidence and onset information
— Based on the latest data available INSULINOMA have a estimated incidence of 0.25 per 100k in Europe.— No data available about the known clinical features onset.
Researches and researchers
Doctors, researchs, and experts related to Insulinoma extracted from public data.
Insulinoma Experts map
Current Researchs and researchers
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Investigator of research project'T HARDE — Mr T. [Ton] VAN DEN HOVEN
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Institution/s:
— SurgVision BV -
Research area/topic::
BETACURE: Personalized diagnosis and treatment of hyperinsulinemic hypoglycaemia caused by beta-cell pathology - NL
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Institution/s:
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Investigator of research projectGRONINGEN — Pr G.M. [Gooitzen] VAN DAM
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Institution/s:
— UMCG - Universitair Medisch Centrum Groningen -
Research area/topic::
BETACURE: Personalized diagnosis and treatment of hyperinsulinemic hypoglycaemia caused by beta-cell pathology - NL
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Institution/s:
Insulinoma Recommended genes panels
Panel Name, Specifity and genes Tested/covered |
---|
![]() By Baylor Miraca Genetics Laboratories (United States).
RGS9, RHO, GRK1, RLBP1, RNASEL, BCS1L, RP1, RP2, RP9, RPE65, RPGR, RPL35A, MRPL3, RPS14, RS1, SAG, SARDH, SCO2, SCP2, SDHB , (...)
View the complete list with 612 more genes
Specificity
1 %
Genes
100 % |
![]() By Baylor Miraca Genetics Laboratories (United States).
TP53, VHL, SUFU, PALB2, ALK, APC, MEN1, MLH1, MRE11, MSH2, MSH6, NBN, NF2, ATM, PMS2, PHOX2B, PTCH1
Specificity
6 %
Genes
100 % |
![]() By Baylor Miraca Genetics Laboratories (United States).
TP53, VHL, SUFU, PALB2, ALK, APC, MEN1, MLH1, MRE11, MSH2, MSH6, NBN, NF2, ATM, PMS2, PHOX2B, PTCH1
Specificity
6 %
Genes
100 % |
![]() By Baylor Miraca Genetics Laboratories (United States).
SDHA, SDHB, SDHC, SDHD, TP53, VHL, CDC73, SDHAF2, TMEM127, MAX, MEN1, PRKAR1A, PTEN, RET
Specificity
8 %
Genes
100 % |
![]() By Baylor Miraca Genetics Laboratories (United States).
RUNX1, SDHA, SDHB, SDHC, SDHD, BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, VHL, WT1, CBL, SUFU, CDC73, CDH1, CDK4, CDKN1C, CDKN2A , (...)
View the complete list with 39 more genes
Specificity
2 %
Genes
100 % |
![]() By Athena Diagnostics Inc (United States).
MEN1
Specificity
100 %
Genes
100 % |
![]() By Center for Human Genetics, Inc (United States).
MEN1
Specificity
100 %
Genes
100 % |
![]() By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States).
BLM, SDHB, BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, TSC1, TSC2, VHL, XRCC2, CDC73, CDH1, CDK4, CDKN1B, CDKN2A, BRIP1, SDHAF2, TMEM127 , (...)
View the complete list with 28 more genes
Specificity
3 %
Genes
100 % |
You can get up to 143 more panels with our dedicated tool
Learn moreSources and references
You can check the following sources for additional information.
ORPHANET Genetic Syndrome FinderIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like PSORIASIS 1, SUSCEPTIBILITY TO; PSORS1 CLUBFOOT, CONGENITAL, WITH OR WITHOUT DEFICIENCY OF LONG BONES AND/OR MIRROR-IMAGE POLYDACTYLY; CCF LETHAL CONGENITAL CONTRACTURE SYNDROME 5; LCCS5