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  3. LANGUAGE DELAY AND ATTENTION DEFICIT-HYPERACTIVITY DISORDER/COGNITIVE IMPAIRMENT WITH OR WITHOUT CARDIAC ARRHYTHMIA; LADCI

Language Delay And Attention Deficit-hyperactivity Disorder/cognitive Impairment With Or Without Cardiac Arrhythmia; Ladci

Table of contents:

Description

LADCI is an autosomal recessive neurodevelopmental disorder characterized by severe expressive and receptive language delay apparent from early childhood. Affected individuals have additional developmental or behavioral abnormalities, including attention deficit, hyperactivity, or mild intellectual disability. Some patients develop cardiac arrhythmias reminiscent of sick sinus syndrome (summary by Lodder et al., 2016 and Shamseldin et al., 2016).

Genes related to Language Delay And Attention Deficit-hyperactivity Disorder/cognitive Impairment With Or Without Cardiac Arrhythmia; Ladci

  • GNB5

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Clinical Features

Top most frequent phenotypes and symptoms related to Language Delay And Attention Deficit-hyperactivity Disorder/cognitive Impairment With Or Without Cardiac Arrhythmia; Ladci

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Delayed speech and language development
  • Motor delay
  • Intellectual disability, mild
  • Arrhythmia
  • Hyperactivity
  • Attention deficit hyperactivity disorder

And another 5 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Language Delay And Attention Deficit-hyperactivity Disorder/cognitive Impairment With Or Without Cardiac Arrhythmia; Ladci Recommended genes panels

Panel Name, Specifity and genes Tested/covered
GNB5.

By Fulgent Genetics Fulgent Genetics (United States).

GNB5
Specificity
100 %
Genes
100 %

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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Search Engine

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