Peeling Skin Syndrome 5; Pss5

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

Peeling skin syndrome-5 (PSS5) is characterized by superficial peeling of the dorsal and palmar skin of the hands and feet; the skin of the forearms and legs may also be involved. Some patients exhibit diffuse yellowish hyperkeratotic palmoplantar plaques (Pigors et al., 2016).For a general phenotypic description and a discussion of genetic heterogeneity of peeling skin syndrome, see PSS1 (OMIM ).

Genes related to Peeling Skin Syndrome 5; Pss5

SERPINB8

View recommended genes panels

Clinical Features

Phenotypes and symptoms related to Peeling Skin Syndrome 5; Pss5

Hyperkeratosis
Erythema
Ichthyosis
Epidermal acanthosis
Scaling skin
Psoriasiform dermatitis

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Peeling Skin Syndrome 5; Pss5 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
SERPINB8. By Institute for Human Genetics University Clinic Freiburg (Germany). SERPINB8 Specificity 100 % Genes 100 %
Epidermolysis bullosa Comprehensive panel. By Connective Tissue Gene Tests (United States). DST, TGM5, FERMT1, CHST8, CDSN, COL17A1, COL7A1, CSTA, KLHL24, DSP, EXPH5, ITGA3, ITGA6, ITGB4, JUP, KRT14, KRT5, LAMA3, LAMB3, LAMC2 , (...) View the complete list with 3 more genes Panel complete gene list DST, TGM5, FERMT1, CHST8, CDSN, COL17A1, COL7A1, CSTA, KLHL24, DSP, EXPH5, ITGA3, ITGA6, ITGB4, JUP, KRT14, KRT5, LAMA3, LAMB3, LAMC2, SERPINB8, PKP1, PLEC Specificity 5 % Genes 100 %
Ichthyosis Deletion / Duplication panel. By Connective Tissue Gene Tests (United States). ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1 , (...) View the complete list with 7 more genes Panel complete gene list ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1, GJB4, ALOX12B, KRT1, KRT10, KRT2, LOR, SERPINB8 Specificity 4 % Genes 100 %
Epidermolysis bullosa NGS panel. By Connective Tissue Gene Tests (United States). DST, TGM5, FERMT1, CHST8, CDSN, COL17A1, COL7A1, CSTA, KLHL24, DSP, EXPH5, ITGA3, ITGA6, ITGB4, JUP, KRT14, KRT5, LAMA3, LAMB3, LAMC2 , (...) View the complete list with 3 more genes Panel complete gene list DST, TGM5, FERMT1, CHST8, CDSN, COL17A1, COL7A1, CSTA, KLHL24, DSP, EXPH5, ITGA3, ITGA6, ITGB4, JUP, KRT14, KRT5, LAMA3, LAMB3, LAMC2, SERPINB8, PKP1, PLEC Specificity 5 % Genes 100 %
Ichthyosis NGS panel. By Connective Tissue Gene Tests (United States). ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1 , (...) View the complete list with 7 more genes Panel complete gene list ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1, GJB4, ALOX12B, KRT1, KRT10, KRT2, LOR, SERPINB8 Specificity 4 % Genes 100 %
Epidermolysis bullosa Deletion / Duplication panel. By Connective Tissue Gene Tests (United States). DST, TGM5, FERMT1, CHST8, CDSN, COL17A1, COL7A1, CSTA, KLHL24, DSP, EXPH5, ITGA3, ITGA6, ITGB4, JUP, KRT14, KRT5, LAMA3, LAMB3, LAMC2 , (...) View the complete list with 3 more genes Panel complete gene list DST, TGM5, FERMT1, CHST8, CDSN, COL17A1, COL7A1, CSTA, KLHL24, DSP, EXPH5, ITGA3, ITGA6, ITGB4, JUP, KRT14, KRT5, LAMA3, LAMB3, LAMC2, SERPINB8, PKP1, PLEC Specificity 5 % Genes 100 %
Ichthyosis Comprehensive panel. By Connective Tissue Gene Tests (United States). ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1 , (...) View the complete list with 7 more genes Panel complete gene list ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1, GJB4, ALOX12B, KRT1, KRT10, KRT2, LOR, SERPINB8 Specificity 4 % Genes 100 %
Peeling skin syndrome NGS panel. By Connective Tissue Gene Tests (United States). TGM5, CAST, CHST8, CDSN, CSTA, FLG2, SERPINB8 Specificity 15 % Genes 100 %

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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Search Engine

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