Premature Ovarian Failure 9; Pof9

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

Nonsyndromic primary ovarian insufficiency, which is characterized by amenorrhea with elevated gonadotropin levels, is observed in 1% of otherwise healthy women under the age of 40 years (summary by Wang et al., 2014).For a general phenotypic description and discussion of the genetic heterogeneity of premature ovarian failure, see POF1 (OMIM ).

Genes related to Premature Ovarian Failure 9; Pof9

HFM1

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Clinical Features

Phenotypes and symptoms related to Premature Ovarian Failure 9; Pof9

Amenorrhea
Premature ovarian insufficiency
Increased circulating gonadotropin level

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Premature Ovarian Failure 9; Pof9 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Premature Ovarian Failure Sequencing Panel. By Genetic Services Laboratory University of Chicago (United States). BMP15, FOXL2, MCM8, PSMC3IP, HFM1, NOBOX, FIGLA, FSHR, LMNA, NR5A1 Specificity 10 % Genes 100 %
Premature Ovarian Failure Deletion/Duplication Panel. By Genetic Services Laboratory University of Chicago (United States). BMP15, FOXL2, MCM8, PSMC3IP, HFM1, NOBOX, FIGLA, FSHR, LMNA, NR5A1 Specificity 10 % Genes 100 %
Premature Ovarian Failure via HFM1 Gene Sequencing with CNV Detection. By PreventionGenetics PreventionGenetics (United States). HFM1 Specificity 100 % Genes 100 %
Female Infertility Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). BMP15, SEMA3A, SEMA3E, FOXL2, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAG3, STAR, TAC3, TACR3, WNT4, WT1, WWOX, ZP1, ARL6 , (...) View the complete list with 84 more genes Panel complete gene list BMP15, SEMA3A, SEMA3E, FOXL2, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAG3, STAR, TAC3, TACR3, WNT4, WT1, WWOX, ZP1, ARL6, WDR11, CBX2, SPRY4, PROKR2, MCM8, TRIM32, IL17RD, PSMC3IP, ARX, PROK2, BBS7, TTC8, HFM1, PADI6, CHD7, CLPP, MCM9, RSPO1, LHX4, NOBOX, FEZF1, FIGLA, MAMLD1, CYP11A1, CYP17A1, CYP19A1, BBS10, BBS12, CCDC141, SOHLH1, DHH, SYCE1, DMRT1, DMRT2, NSMF, NUP107, BBS9, DUSP6, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, AIRE, FGF17, FGF8, FGFR1, FGFR2, FLRT3, AKR1C4, FSHB, FSHR, GALT, GNRH1, GNRHR, KISS1R, HESX1, HFE, HS6ST1, HSD17B3, ANOS1, KISS1, AR, LEP, LEPR, LHB, LHCGR, LHX3, LMNA, MAP3K1, MKKS, NR0B1, NR3C1, NR5A1, PCSK1, ATRX, AXL, POR, PRLR, PROP1, BBS1, BBS2, BBS4, BBS5 Specificity 1 % Genes 100 %
Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). ROR2, SALL1, BMP15, BMP4, SEMA3A, SEMA3E, BMP7, FOXL2, BRDT, SOS1, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAG3, STAR, AURKC , (...) View the complete list with 187 more genes Panel complete gene list ROR2, SALL1, BMP15, BMP4, SEMA3A, SEMA3E, BMP7, FOXL2, BRDT, SOS1, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAG3, STAR, AURKC, TAC3, TACR3, TAF4B, TBX15, HNF1B, TEX11, MED12, CEP41, TSPYL1, WNT4, WNT5A, WNT7A, WT1, WWOX, ZP1, ARL6, FBXL4, WDR11, SLC26A8, ZEB2, CBX2, SPRY4, SETBP1, PROKR2, TOE1, TP63, PCNT, MCM8, SUN5, TRIM32, ZFPM2, UBR1, FIG4, CATSPER1, IL17RD, CDKN1C, PSMC3IP, ARX, SYCP3, HHAT, PROK2, GRIP1, BBS7, KLHL10, CFTR, FRAS1, CHD4, PLCZ1, EVC2, TTC8, HFM1, B3GLCT, PADI6, CHD7, TWIST2, CLPP, BCOR, ZMYND15, CUL7, ICK, MCM9, RSPO1, GALNTL5, LHX4, WDR60, NOBOX, FEZF1, NANOS1, FAT4, CREBBP, FIGLA, FREM2, CFAP44, MAMLD1, CYB5A, CYP11A1, CYP11B1, CYP17A1, CYP19A1, TMEM70, BBS10, SEPT12, BBS12, CFAP43, CCDC141, ESCO2, SOHLH1, CCNQ, DHCR24, DHCR7, DHH, SYCE1, SPECC1L, WDR35, EPG5, DMRT1, DMRT2, DNAH1, DYNC2H1, DNMT3B, NSMF, NUP107, SPATA16, BBS9, DUSP6, TRAIP, BNC2, EFNB1, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, EVC, AIRE, FGF10, FGF17, FGF8, FGFR1, FGFR2, FGFR3, FLNA, FLRT3, AKR1C4, FSHB, FSHR, GALT, GATA4, GLI3, GNRH1, GNRHR, GPC3, KISS1R, ADGRG2, AMH, AMHR2, HBA1, HCCS, HESX1, HFE, RIPK4, HOXA13, HOXA4, HOXB6, HS6ST1, HSD17B3, HSD17B4, HSD3B2, INSL3, IRF6, ANOS1, KISS1, AR, LEP, LEPR, LHB, LHCGR, LHX3, LMNA, MAP3K1, MID1, MKKS, MKS1, NEK1, ATF3, NPAS2, NR0B1, NR3C1, NR5A1, OPHN1, PCSK1, PDE4D, PEX1, ATRX, PITX2, AXL, POR, PICK1, PRLR, PROP1, PTDSS1, PTPN11, BBS1, BBS2, BBS4, BBS5, RBBP8 Specificity 1 % Genes 100 %
Premature Ovarian Failure (POF) Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). BMP15, FOXL2, STAG3, MCM8, PSMC3IP, HFM1, CLPP, MCM9, NOBOX, FIGLA, CYP17A1, CYP19A1, SOHLH1, EIF2B2, EIF2B4, EIF2B5, AIRE, FSHR, GALT, LMNA , (...) View the complete list with 1 more genes Panel complete gene list BMP15, FOXL2, STAG3, MCM8, PSMC3IP, HFM1, CLPP, MCM9, NOBOX, FIGLA, CYP17A1, CYP19A1, SOHLH1, EIF2B2, EIF2B4, EIF2B5, AIRE, FSHR, GALT, LMNA, NR5A1 Specificity 5 % Genes 100 %
HFM1. By Fulgent Genetics Fulgent Genetics (United States). HFM1 Specificity 100 % Genes 100 %
Premature Ovarian Failure: Sequencing Panel and FMR1 CGG Repeat Analysis. By CEN4GEN Institute for Genomics and Molecular Diagnostics (Canada). BMP15, FOXL2, POF1B, PSMC3IP, HFM1, NOBOX, FIGLA, CYP17A1, CYP19A1, DIAPH2, EIF2B2, EIF2B3, EIF2B5, FMR1, FSHR, GALT, GDF9, LHCGR, LMNA, NR5A1 , (...) View the complete list with 1 more genes Panel complete gene list BMP15, FOXL2, POF1B, PSMC3IP, HFM1, NOBOX, FIGLA, CYP17A1, CYP19A1, DIAPH2, EIF2B2, EIF2B3, EIF2B5, FMR1, FSHR, GALT, GDF9, LHCGR, LMNA, NR5A1, POR Specificity 5 % Genes 100 %

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Sources and references

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