1. Mendelian
  2. Rare Diseases
  3. SPASTIC PARAPLEGIA 19, AUTOSOMAL DOMINANT; SPG19

Autosomal Dominant Spastic Paraplegia Type 19

Table of contents:

Description

Autosomal dominant spastic paraplegia type 19 is a pure form of hereditary spastic paraplegia characterized by a slowly progressive and relatively benign spastic paraplegia presenting in adulthood with spastic gait, lower limb hyperreflexia, extensor plantar responses, bladder dysfunction (urinary urgency and/or incontinence), and mild sensory and motor peripheral neuropathy.

Genes related to Autosomal Dominant Spastic Paraplegia Type 19

  • SPG19

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Clinical Features

Top most frequent phenotypes and symptoms related to Autosomal Dominant Spastic Paraplegia Type 19

  • Seizures
  • Spasticity
  • Hyperreflexia
  • Babinski sign
  • Difficulty walking
  • Anxiety
  • Spastic paraplegia
  • Paraplegia
  • Lower limb muscle weakness
  • Muscle cramps

And another 24 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Based on the latest data available there are 1 families with AUTOSOMAL DOMINANT SPASTIC PARAPLEGIA TYPE 19 in Europe.
— No data available about the known clinical features onset.

Alternative names

Autosomal Dominant Spastic Paraplegia Type 19 Is also known as spg19.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Sources and references

You can check the following sources for additional information.

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