1. Mendelian
  2. Rare Diseases
  3. SPASTIC PARAPLEGIA 36, AUTOSOMAL DOMINANT; SPG36

Autosomal Dominant Spastic Paraplegia Type 36

Table of contents:

Description

Autosomal dominant spastic paraplegia type 36 (SPG36) is a complex form of hereditary spastic paraplegia, characterized by an onset in childhood or adulthood of progressive spastic paraplegia (with spastic gait, spasticity, lower limb weakness, pes cavus and urinary urgency) associated with the additional manifestation of peripheral sensorimotor neuropathy.

Genes related to Autosomal Dominant Spastic Paraplegia Type 36

  • SPG36

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Clinical Features

Top most frequent phenotypes and symptoms related to Autosomal Dominant Spastic Paraplegia Type 36

  • Strabismus
  • Spasticity
  • Peripheral neuropathy
  • Hyperreflexia
  • Babinski sign
  • Pes cavus
  • Dementia
  • Proximal muscle weakness
  • Arthritis
  • Distal muscle weakness

And another 18 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Based on the latest data available there are 1 families with AUTOSOMAL DOMINANT SPASTIC PARAPLEGIA TYPE 36 in Europe.
— No data available about the known clinical features onset.

Alternative names

Autosomal Dominant Spastic Paraplegia Type 36 Is also known as spg36.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Sources and references

You can check the following sources for additional information.

ORPHANET OMIM MESH Genetic Syndrome Finder

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