Tooth Agenesis, Selective, 1; Sthag1
Description
Tooth agenesis in some form is a common human anomaly that affects approximately 20% of the population. Although tooth agenesis is associated with numerous syndromes, several case reports describe nonsyndromic forms that are either sporadic or familial in nature, as reviewed by Gorlin et al. (1990). The incidence of familial tooth agenesis varies with each class of teeth. Most commonly affected are third molars (wisdom teeth), followed by either upper lateral incisors or lower second premolars; agenesis involving first and second molars is very rare. Also see {114600} and {302400}.Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and hypodontia, defined as agenesis of less than 6 teeth. The number in both cases does not include absence of third molars (wisdom teeth). Faulty use of the terms, however, have confounded their use. The term 'partial anodontia' is obsolete (Salinas, 1978).
Clinical Features
Phenotypes and symptoms related to Tooth Agenesis, Selective, 1; Sthag1
- Short stature
- Abnormality of the dentition
- Hypodontia
- Oligodontia
- Reduced number of teeth
- Anodontia
- Selective tooth agenesis
Incidence and onset information
— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)— No data available about the known clinical features onset.
Alternative names
Tooth Agenesis, Selective, 1; Sthag1 Is also known as hyd1, hypodontia/oligodontia 1, second premolars and third molars, absence of, tooth agenesis, familial.
Researches and researchers
Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.Tooth Agenesis, Selective, 1; Sthag1 Recommended genes panels
Panel Name, Specifity and genes Tested/covered |
---|
Orofacial cleft 5 (sequence analysis of MSX1 gene).
By CGC Genetics (Portugal).
MSX1
Specificity
100 %
Genes
100 % |
Ectodermal dysplasia (NGS panel for 8 genes).
By CGC Genetics (Portugal).
EDARADD, KRT74, EDAR, EDA, GJB6, HOXC13, KRT85, MSX1
Specificity
13 %
Genes
100 % |
Ectodermal dysplasia (NGS panel for 8 genes).
By CGC Genetics (Portugal).
EDARADD, KRT74, EDAR, EDA, GJB6, HOXC13, KRT85, MSX1
Specificity
13 %
Genes
100 % |
Ectodermal Dysplasia/Tooth Agenesis via MSX1 Gene Sequencing with CNV Detection.
By PreventionGenetics PreventionGenetics (United States).
MSX1
Specificity
100 %
Genes
100 % |
Tooth Agenesis Sequencing Panel with CNV Detection.
By PreventionGenetics PreventionGenetics (United States).
WNT10A, EDARADD, EDAR, EDA, LTBP3, MSX1, PAX9, AXIN2
Specificity
13 %
Genes
100 % |
Cleft lip, cleft palate and related disorders NGS panel.
By Connective Tissue Gene Tests (United States).
BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1
Specificity
7 %
Genes
100 % |
Cleft lip, cleft palate and related disorders Deletion / Duplication panel.
By Connective Tissue Gene Tests (United States).
BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1
Specificity
7 %
Genes
100 % |
Cleft lip, cleft palate and related disorders Comprehensive panel.
By Connective Tissue Gene Tests (United States).
BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1
Specificity
7 %
Genes
100 % |
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Learn moreSources and references
You can check the following sources for additional information.
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