DRD3 gene related symptoms and diseases
All the information presented here about the DRD3 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to DRD3 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Anxiety | Very Common - Between 80% and 100% cases |
| Depressivity | Very Common - Between 80% and 100% cases |
| Behavioral abnormality | Common - Between 50% and 80% cases |
| Migraine | Common - Between 50% and 80% cases |
| Abnormality of extrapyramidal motor function | Common - Between 50% and 80% cases |
Other less frequent symptoms and clinical features
Patients with DRD3 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Rigidity
- Abnormality of movement
- Autism
- Dementia
Not very common - Between 30% and 50% cases
- Mental deterioration
- Parkinsonism
- Memory impairment
- Small for gestational age
And 70 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to DRD3 gene
Here you will find a list of rare diseases related to the DRD3. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
GILLES DE LA TOURETTE SYNDROME; GTS
Alternate names
GILLES DE LA TOURETTE SYNDROME; GTS Is also known as ts, tourette syndrome, tourette disorder
Description
Tourette syndrome is a neurobehavioral disorder manifest particularly by motor and vocal tics and associated with behavioral abnormalities. Tics are sudden, brief, intermittent, involuntary or semi-voluntary movements (motor tics) or sounds (phonic or vocal tics). They typically consist of simple, coordinated, repetitive movements, gestures, or utterances that mimic fragments of normal behavior. Motor tics may range from simple blinking, nose twitching, and head jerking to more complex throwing, hitting, or making rude gestures. Phonic tics include sniffling, throat clearing, blowing, coughing, echolalia, or coprolalia. Males are affected about 3 times more often than females, and onset usually occurs between 3 and 8 years of age. By age 18 years, more than half of affected individuals are free of tics, but they may persist into adulthood (review by Jankovic, 2001).
Most common symptoms of GILLES DE LA TOURETTE SYNDROME; GTS
- Behavioral abnormality
- Depressivity
- Pectus excavatum
- Myoclonus
- Hyperactivity
More info about GILLES DE LA TOURETTE SYNDROME; GTS
TREMOR, HEREDITARY ESSENTIAL, 1; ETM1
Alternate names
TREMOR, HEREDITARY ESSENTIAL, 1; ETM1 Is also known as fet1, tremor, familial essential, 1
Description
Essential tremor may be the most common human movement disorder. The main feature of essential tremor is postural tremor of the arms, but the head, legs, trunk, voice, jaw, and facial muscles also may be involved. Aggravated by emotions, hunger, fatigue, and temperature extremes, the condition may cause a functional disability or even incapacitation. Autosomal dominant inheritance can be demonstrated in most families (summary by Higgins et al., 1997).Deng et al. (2007) provided a detailed review of the genetics of essential tremor.
Most common symptoms of TREMOR, HEREDITARY ESSENTIAL, 1; ETM1
- Hearing impairment
- Ataxia
- Cognitive impairment
- Dysarthria
- Fever
More info about TREMOR, HEREDITARY ESSENTIAL, 1; ETM1
SOURCES: OMIM
SCHIZOPHRENIA; SCZD
Alternate names
SCHIZOPHRENIA; SCZD Is also known as schizophrenia with or without an affective disorder
Description
Schizophrenia is a psychosis, a disorder of thought and sense of self. Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. There is no characteristic pathology, such as neurofibrillary tangles in Alzheimer disease (OMIM ). Schizophrenia is a common disorder with a lifetime prevalence of approximately 1%. It is highly heritable but the genetics are complex. This may not be a single entity.Schizophrenia and bipolar disorder (see {125480}) are generally considered to be separate entities, but patients who exhibit multiple symptoms of both disorders are often given the hybrid diagnosis schizoaffective disorder (Blacker and Tsuang, 1992).
Most common symptoms of SCHIZOPHRENIA; SCZD
- Intellectual disability
- Microcephaly
- Behavioral abnormality
- Depressivity
- Dementia
More info about SCHIZOPHRENIA; SCZD
SOURCES: OMIM
Search interest in DRD3
Potential gene panels for DRD3 gene
DRD3. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the DRD3 gene.
More info about this panel Spain.
Hereditary essential tremor (sequence analysis of DRD3 gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the DRD3 gene.
More info about this panel Portugal.
AllNeuro panel Panel
Germany.
By Centogene AG - the Rare Disease Company AllNeuro panel that also includes the following genes: BCS1L ROR2 RPL10 BDNF RPS6KA3 RTN2 RYR1 SACS BIN1 SBF1
More info about this panel Germany.
DRD3 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the DRD3 gene.
More info about this panel United States.
Schizophrenia, susceptibility to Panel
Spain.
By Bioarray
This panel specifically test the DRD3 gene.
More info about this panel Spain.
Schizophrenia Susceptibility to , Sequencing DRD3 Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the DRD3 gene.
More info about this panel Spain.
Hereditary Essential Tremor, Panel Massive Sequencing (NGS) DRD3, TENM4, FUS Genes Panel
Spain.
By Reference Laboratory Genetics Hereditary Essential Tremor, Panel Massive Sequencing (NGS) DRD3, TENM4, FUS Genes that also includes the following genes: TENM4 DRD3 FUS
More info about this panel Spain.
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