HLA-DQA1 gene related symptoms and diseases
All the information presented here about the HLA-DQA1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,ORPHANET,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to HLA-DQA1 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Vomiting | Common - Between 50% and 80% cases |
| Weight loss | Common - Between 50% and 80% cases |
| Pain | Uncommon - Between 30% and 50% cases |
| Chronic diarrhea | Uncommon - Between 30% and 50% cases |
| Rickets | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with HLA-DQA1 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Abnormal intestine morphology
- Spontaneous abortion
- Type I diabetes mellitus
- Hypocalcemia
- Inflammatory abnormality of the skin
- Hypoplasia of dental enamel
- Malnutrition
- Eczema
And 58 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to HLA-DQA1 gene
Here you will find a list of rare diseases related to the HLA-DQA1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
IDIOPATHIC ACHALASIA
Alternate names
IDIOPATHIC ACHALASIA Is also known as idiopathic achalasia of esophagus, achalasia cardia, primary achalasia
Description
Idiopathic achalasia (IA) is a primary esophageal motor disorder characterized by loss of esophageal peristalsis and insufficient lower esophageal sphincter (LES) relaxation in response to deglutition.
Most common symptoms of IDIOPATHIC ACHALASIA
- Pain
- Dysphagia
- Vomiting
- Weight loss
- Gastroesophageal reflux
More info about IDIOPATHIC ACHALASIA
CELIAC DISEASE, SUSCEPTIBILITY TO, 1; CELIAC1
Alternate names
CELIAC DISEASE, SUSCEPTIBILITY TO, 1; CELIAC1 Is also known as celiac sprue, susceptibility to, 1, gluten-sensitive enteropathy, susceptibility to, 1
Description
Celiac disease, also known as celiac sprue and gluten-sensitive enteropathy (GSE), is a multifactorial disorder of the small intestine that is influenced by both environmental and genetic factors. It is characterized by malabsorption resulting from inflammatory injury to the mucosa of the small intestine after the ingestion of wheat gluten or related rye and barley proteins (summary by Farrell and Kelly, 2002). Long regarded as gastrointestinal disorder of childhood, the disease is now considered to be a chronic systemic autoimmune disease and is more often diagnosed in adults than in children (Monsuur et al., 2005).For a discussion of genetic heterogeneity of celiac disease, see MAPPING.
Most common symptoms of CELIAC DISEASE, SUSCEPTIBILITY TO, 1; CELIAC1
- Seizures
- Short stature
- Ataxia
- Failure to thrive
- Anemia
More info about CELIAC DISEASE, SUSCEPTIBILITY TO, 1; CELIAC1
SOURCES: OMIM
ADULT-ONSET MYASTHENIA GRAVIS
Alternate names
ADULT-ONSET MYASTHENIA GRAVIS Is also known as adult-onset acquired myasthenia, adult-onset autoimmune myasthenia gravis
Description
Acquired myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction characterized by fatigable muscle weakness with frequent ocular signs and/or generalized muscle weakness, and occasionally associated with thymoma (see this term).
More info about ADULT-ONSET MYASTHENIA GRAVIS
SOURCES: ORPHANET
Search interest in HLA-DQA1
Potential gene panels for HLA-DQA1 gene
Celiac Disease (HLA-DQ2 and HLA-DQ8) Genotyping Panel
United States.
By ARUP Laboratories, Molecular Genetics and Genomics Celiac Disease (HLA-DQ2 and HLA-DQ8) Genotyping that also includes the following genes: HLA-DQA1 HLA-DQB1
More info about this panel United States.
Celiac disease (HLA-DQ/DR) Panel
Portugal.
By CGC Genetics Celiac disease (HLA-DQ/DR) that also includes the following genes: HLA-DQA1 HLA-DQB1
More info about this panel Portugal.
Lactose intolerance (MCM6 gene) and Celiac disease (HLA-DQ2/ HLA-DQ8) Panel
Portugal.
By CGC Genetics Lactose intolerance (MCM6 gene) and Celiac disease (HLA-DQ2/ HLA-DQ8) that also includes the following genes: HLA-DQA1 HLA-DQB1 MCM6
More info about this panel Portugal.
Celiac Disease via Next Generation Sequencing HLA Typing Panel
United States.
By PreventionGenetics PreventionGenetics Celiac Disease via Next Generation Sequencing HLA Typing that also includes the following genes: HLA-DQA1 HLA-DQB1
More info about this panel United States.
HLA DQ2/DQ8 Panel
Norway.
By Furst Medical Laboratories, FurstNAT HLA DQ2/DQ8 that also includes the following genes: HLA-DQA1 HLA-DQB1
More info about this panel Norway.
Celiac Disease (HLA-DQA1*05, HLA-DQB1*02, and HLA-DQB1*03:02) Genotyping Panel
Argentina.
By Molecular Genetics Laboratory Centro de Investigaciones Endocrinologicas "Dr. Cesar Bergada" Celiac Disease (HLA-DQA1*05, HLA-DQB1*02, and HLA-DQB1*03:02) Genotyping that also includes the following genes: HLA-DQA1 HLA-DQB1
More info about this panel Argentina.
HLA-DQA1 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the HLA-DQA1 gene.
More info about this panel United States.
Tempus xT assay Panel
United States.
By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA
More info about this panel United States.
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