LPAR6 gene related symptoms and diseases
All the information presented here about the LPAR6 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,ORPHANET,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to LPAR6 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Hyperhidrosis | Very Common - Between 80% and 100% cases |
| Sparse body hair | Very Common - Between 80% and 100% cases |
| Alopecia | Common - Between 50% and 80% cases |
| Hyperkeratosis | Common - Between 50% and 80% cases |
| Dry hair | Common - Between 50% and 80% cases |
Other less frequent symptoms and clinical features
Patients with LPAR6 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Woolly hair
- Fair hair
- Curly hair
- Brittle hair
- Coarse hair
- Palmoplantar hyperkeratosis
- Trichorrhexis nodosa
- Sparse axillary hair
And 31 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to LPAR6 gene
Here you will find a list of rare diseases related to the LPAR6. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
HYPOTRICHOSIS SIMPLEX
Alternate names
HYPOTRICHOSIS SIMPLEX Is also known as hhs, hereditary hypotrichosis simplex, hts, hypotrichosis simplex, generalized, hereditary
Description
Hypotrichosis simplex (HS) or hereditary hypotrichosis simplex (HHS) is characterized by reduced pilosity over the scalp and body (with sparse, thin, and short hair) in the absence of other anomalies.
Most common symptoms of HYPOTRICHOSIS SIMPLEX
- Alopecia
- Hyperhidrosis
- Sparse hair
- Hypotrichosis
- Sparse and thin eyebrow
More info about HYPOTRICHOSIS SIMPLEX
HYPOTRICHOSIS 8; HYPT8
Alternate names
HYPOTRICHOSIS 8; HYPT8 Is also known as lah3, hypotrichosis, localized, autosomal recessive 3
Description
Hypotrichosis simplex refers to a group of hereditary isolated alopecias characterized by diffuse and progressive hair loss, usually beginning in early childhood (Pasternack et al., 2008). Localized autosomal recessive hypotrichosis (LAH) is characterized by fragile hairs that break easily, leaving short, sparse scalp hairs. The disorder affects the trunk and extremities as well as the scalp, and the eyebrows and eyelashes may also be involved, whereas beard, pubic, and axillary hairs are largely spared. In addition, patients can develop hyperkeratotic follicular papules, erythema, and pruritus in affected areas (summary by Schaffer et al., 2006).Woolly hair (WH) refers to a group of hair shaft disorders that are characterized by fine and tightly curled hair. Compared to normal curly hair that is observed in some populations, WH grows slowly and stops growing after a few inches. Under light microscopy, WH shows some structural anomalies, including trichorrhexis nodosa and tapered ends (summary by Petukhova et al., 2009). Several families have been reported in which some affected individuals exhibit features of hypotrichosis and others have woolly scalp hair (Khan et al., 2011).Woolly hair is also a feature of several syndromes, such as Naxos disease (OMIM ) and cardiofaciocutaneous syndrome (OMIM ) (Petukhova et al., 2009), or the palmoplantar keratoderma and cardiomyopathy syndrome (OMIM ) (Carvajal-Huerta, 1998).
Most common symptoms of HYPOTRICHOSIS 8; HYPT8
- Cardiomyopathy
- Alopecia
- Hyperhidrosis
- Hyperkeratosis
- Erythema
More info about HYPOTRICHOSIS 8; HYPT8
WOOLLY HAIR
Alternate names
WOOLLY HAIR Is also known as wooly hair, familial woolly hair syndrome, hereditary woolly hair syndrome, familial wooly hair syndrome, hereditary wooly hair syndrome
Description
Woolly hair is a rare congenital abnormality of the structure of the scalp hair marked by extreme kinkiness of the hair.
Most common symptoms of WOOLLY HAIR
- Strabismus
- Cataract
- Hyperhidrosis
- Hyperkeratosis
- Nevus
More info about WOOLLY HAIR
Search interest in LPAR6
Potential gene panels for LPAR6 gene
Hypotrichosis simplex, type 8 (sequence analysis of LPAR6 gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the LPAR6 gene.
More info about this panel Portugal.
Hypotrichosis (NGS panel of 10 genes) Panel
Portugal.
By CGC Genetics Hypotrichosis (NGS panel of 10 genes) that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR
More info about this panel Portugal.
Hypotrichosis (NGS panel of 10 genes) Panel
Portugal.
By CGC Genetics Hypotrichosis (NGS panel of 10 genes) that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR
More info about this panel Portugal.
Hypotrichosis Comprehensive panel Panel
United States.
By Connective Tissue Gene Tests Hypotrichosis Comprehensive panel that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR
More info about this panel United States.
Hypotrichosis NGS panel Panel
United States.
By Connective Tissue Gene Tests Hypotrichosis NGS panel that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR
More info about this panel United States.
Hypotrichosis Deletion / Duplication panel Panel
United States.
By Connective Tissue Gene Tests Hypotrichosis Deletion / Duplication panel that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR
More info about this panel United States.
Hypotrichosis type 8 Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the LPAR6 gene.
More info about this panel Germany.
Nonsyndromic hypotrichosis panel Panel
Germany.
By Centogene AG - the Rare Disease Company Nonsyndromic hypotrichosis panel that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR
More info about this panel Germany.
Ectodermal dysplasia (including hypotrichosis and hypoplastic hair) Panel Panel
Germany.
By CeGaT GmbH Ectodermal dysplasia (including hypotrichosis and hypoplastic hair) Panel that also includes the following genes: BCS1L SNRPE SOX18 ST14 TRPS1 IFT122 WNT10A EDARADD SHOC2 LPAR6
More info about this panel Germany.
LPAR6 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the LPAR6 gene.
More info about this panel United States.
HYPOTRICHOSIS SIMPLEX Panel
Spain.
By Laboratorio de Genetica Clinica SL HYPOTRICHOSIS SIMPLEX that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 LIPH DSG4 KRT71 KRT74 KRT25
More info about this panel Spain.
Woolly hair Panel
Spain.
By Laboratorio de Genetica Clinica SL Woolly hair that also includes the following genes: LPAR6 LIPH KRT71 KRT74 KRT25
More info about this panel Spain.
Woolly hair/Hypothricosis Simplex: NGS Panel Panel
Spain.
By Laboratorio de Genetica Clinica SL Woolly hair/Hypothricosis Simplex: NGS Panel that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 KRT25
More info about this panel Spain.
Hypotricosis , Panel Massive Sequencing (NGS) 8 Genes Panel
Spain.
By Reference Laboratory Genetics Hypotricosis , Panel Massive Sequencing (NGS) 8 Genes that also includes the following genes: RPL21 LPAR6 APCDD1 CDSN LIPH DSG4 KRT74 HR
More info about this panel Spain.
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