SLCO1B1 gene related symptoms and diseases
All the information presented here about the SLCO1B1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,HGNC,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to SLCO1B1 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Fever | Very Common - Between 80% and 100% cases |
| Abdominal pain | Very Common - Between 80% and 100% cases |
| Jaundice | Very Common - Between 80% and 100% cases |
| Conjugated hyperbilirubinemia | Very Common - Between 80% and 100% cases |
| Abnormality of the gastric mucosa | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with SLCO1B1 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Hepatomegaly
- Fatigue
- Abnormality of the skeletal system
- Abnormality of skin pigmentation
- Hyperbilirubinemia
- Abnormality of coagulation
- Biliary tract abnormality
- Abnormal urinary color
Rare diseases associated to SLCO1B1 gene
Here you will find a list of rare diseases related to the SLCO1B1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
ROTOR SYNDROME
Alternate names
ROTOR SYNDROME Is also known as hyperbilirubinemia, rotor type
Description
Rotor syndrome (RT) is a benign, inherited liver disorder characterized by chronic, predominantly conjugated, nonhemolytic hyperbilirubinemia with normal liver histology.
Most common symptoms of ROTOR SYNDROME
- Fever
- Abdominal pain
- Jaundice
- Conjugated hyperbilirubinemia
- Abnormality of the gastric mucosa
More info about ROTOR SYNDROME
SOURCES: ORPHANET
HYPERBILIRUBINEMIA, ROTOR TYPE; HBLRR
Alternate names
HYPERBILIRUBINEMIA, ROTOR TYPE; HBLRR Is also known as rotor syndrome
Description
The Rotor type of hyperbilirubinemia is an autosomal recessive form of primary conjugated hyperbilirubinemia. It is similar to Dubin-Johnson syndrome (DJS ) in that affected individuals develop mild jaundice not associated with hemolysis shortly after birth or in childhood. However, Rotor syndrome can be distinguished from DJS by a lack of hepatocyte pigment deposits, delayed plasma clearance of the unconjugated anionic dye bromsulfthalein, poor hepatic visualization on certain radiographic imaging studies, and prominent urinary excretion of coproporphyrin I (summary by van de Steeg et al., 2012).
Most common symptoms of HYPERBILIRUBINEMIA, ROTOR TYPE; HBLRR
- Hepatomegaly
- Fever
- Fatigue
- Abnormality of the skeletal system
- Abdominal pain
More info about HYPERBILIRUBINEMIA, ROTOR TYPE; HBLRR
SOURCES: OMIM
Search interest in SLCO1B1
Potential gene panels for SLCO1B1 gene
Hereditary Hemolytic Anemia Panel, Sequencing Panel
United States.
By ARUP Laboratories, Molecular Genetics and Genomics Hereditary Hemolytic Anemia Panel, Sequencing that also includes the following genes: SLCO1B1 SLCO1B3 SPTA1 SPTB TPI1 UGT1A1 UGT1A6 UGT1A7 NT5C3A ADA
More info about this panel United States.
Statin-induced myopathy Panel
Brazil.
By GENE Núcleo de Genética Médica de Minas Gerais
This panel specifically test the SLCO1B1 gene.
More info about this panel Brazil.
FHNext Panel
United States.
By Ambry Genetics FHNext that also includes the following genes: SLCO1B1 LDLRAP1 PCSK9 LDLR
More info about this panel United States.
Dyslipidemia NGS panel (29 genes), Sequence & CNV analysis Panel
Netherlands.
By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam Dyslipidemia NGS panel (29 genes), Sequence & CNV analysis that also includes the following genes: SAR1B SLCO1B1 ABCG5 ABCG8 LMF1 SCARB1 APOA5 LDLRAP1 CETP PCSK9
More info about this panel Netherlands.
SLCO1B1. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the SLCO1B1 gene.
More info about this panel Spain.
Hyperbilirubinemia, Rotor type (sequence analysis of SLCO1B1 and SLCO1B3 gene) Panel
Portugal.
By CGC Genetics Hyperbilirubinemia, Rotor type (sequence analysis of SLCO1B1 and SLCO1B3 gene) that also includes the following genes: SLCO1B1 SLCO1B3
More info about this panel Portugal.
Hyperbilirubinemia, Rotor type (sequence analysis of SLCO1B1 gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the SLCO1B1 gene.
More info about this panel Portugal.
Rotor Syndrome via SLCO1B1 Gene Sequencing with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics
This panel specifically test the SLCO1B1 gene.
More info about this panel United States.
Rotor Syndrome Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Rotor Syndrome Sequencing Panel with CNV Detection that also includes the following genes: SLCO1B1 SLCO1B3
More info about this panel United States.
Hepatic and pancreatic diseases - panels Panel
Germany.
By MGZ Medical Genetics Center Hepatic and pancreatic diseases - panels that also includes the following genes: SLCO1B1 SLCO1B3 SLC25A13 SLC27A5 SMPD1 HNF1B TJP2 UROD UROS VPS33B
More info about this panel Germany.
Statin induced myopathy Panel
Germany.
By Synlab MVZ Humane Genetik München Synlab MVZ Humane Genetik München
This panel specifically test the SLCO1B1 gene.
More info about this panel Germany.
Hyperbilirubinemia, Rotor type, digenic Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the SLCO1B1 gene.
More info about this panel Germany.
CentoICU platinum plus Panel
Germany.
By Centogene AG - the Rare Disease Company CentoICU platinum plus that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panel Germany.
New Born testing (CentoICU) Panel
Germany.
By Centogene AG - the Rare Disease Company New Born testing (CentoICU) that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panel Germany.
Pharmacogenetic panel Panel
Germany.
By bio.logis Center for Human Genetics Diagnosticum Pharmacogenetic panel that also includes the following genes: SLC19A1 SLCO1B1 SOD2 TPMT UGT1A1 CCR5 VKORC1 ADH1B CYP2B6 CYP2C19
More info about this panel Germany.
Statin-Induced Myopathy Panel
Estonia.
By Asper Biogene Asper Biogene LLC
This panel specifically test the SLCO1B1 gene.
More info about this panel Estonia.
Cardiovascular Diseases_General Panel Panel
Spain.
By Health in Code Cardiovascular Diseases_General Panel that also includes the following genes: RIT1 MRPL3 RRAS RYR1 RYR2 SAR1B BLK SCN10A SCN1B SCN2B
More info about this panel Spain.
Familialhypercholesterolemia Basic Panel Panel
Spain.
By Health in Code Familialhypercholesterolemia Basic Panel that also includes the following genes: SLCO1B1 LDLRAP1 PCSK9 APOE LDLR
More info about this panel Spain.
Dyslipidemias / Early atherosclerosis Panel
Spain.
By Health in Code Dyslipidemias / Early atherosclerosis that also includes the following genes: RYR1 SAR1B BLK SLCO1B1 SLC22A8 SLC2A2 HNF1A HNF1B KLF11 WFS1
More info about this panel Spain.
Familialhypercholesterolemia Extended Panel Panel
Spain.
By Health in Code Familialhypercholesterolemia Extended Panel that also includes the following genes: RYR1 SLCO1B1 SLC22A8 ABCG5 ABCG8 LDLRAP1 CH25H PCSK9 CPT2 COQ2
More info about this panel Spain.
SLCO1B1 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the SLCO1B1 gene.
More info about this panel United States.
YouScript Cardio Panel
United States.
By Genelex YouScript Cardio that also includes the following genes: SLCO1B1 VKORC1 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5 F2 F5 MTHFR
More info about this panel United States.
SLCO1B1 Panel
United States.
By Genelex
This panel specifically test the SLCO1B1 gene.
More info about this panel United States.
Genetic study of Simvastatin pharmacogenetics Panel
Portugal.
By HeartGenetics, Genetics and Biotechnology, SA
This panel specifically test the SLCO1B1 gene.
More info about this panel Portugal.
Hyperbilirubinemia, Rotor type, digenic Panel
Spain.
By Bioarray
This panel specifically test the SLCO1B1 gene.
More info about this panel Spain.
Comprehensive Pharmacogenomics (PGX) Panel Panel
United States.
By ApolloGen, Inc. Comprehensive Pharmacogenomics (PGX) Panel that also includes the following genes: SLCO1B1 VKORC1 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5 F5 HTR2A MTHFR
More info about this panel United States.
Next Generation Sequencing for Jaundice Associated Genes Variation Test Panel
Taiwan.
By National Taiwan University Hospital A1 Center National Taiwan University Hospital Next Generation Sequencing for Jaundice Associated Genes Variation Test that also includes the following genes: BCS1L SCO1 SLC10A1 SLC40A1 SLCO1A2 SLCO1B1 SLCO1B3 SLCO2B1 SLC25A13 SUCLG1
More info about this panel Taiwan.
Medication Response Genetic Test Panel
United States.
By Color Medication Response Genetic Test that also includes the following genes: SLCO1B1 TPMT IFNL3 NUDT15 VKORC1 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5
More info about this panel United States.
OneOme RightMed comprehensive test Panel
United States.
By OneOme OneOme RightMed comprehensive test that also includes the following genes: SLCO1B1 SLC6A4 TPMT UGT1A1 IFNL3 NUDT15 VKORC1 CYP2B6 CYP2C18 CYP2C19
More info about this panel United States.
Rxight Pharmacogenetics Program Panel
United States.
By MD Labs MD Labs Rxight Pharmacogenetics Program that also includes the following genes: SLCO1B1 TPMT UGT2B15 ANKK1 VKORC1 CYP2B6 CYP2C19 CYP2C8 CYP2C9 CYP2D6
More info about this panel United States.
SLCO1B1 genotyping Panel
United States.
By Alpha Genomix Laboratories
This panel specifically test the SLCO1B1 gene.
More info about this panel United States.
Rotor Syndrome, Sequencing SLCO1B1 Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the SLCO1B1 gene.
More info about this panel Spain.
PharmacoScan Panel
United States.
By RPRD Diagnostics, LLC RPRD Diagnostics, LLC PharmacoScan that also includes the following genes: SLCO1B1 TPMT UGT1A1 VKORC1 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5 DPYD
More info about this panel United States.
152 Integrated Advantage NGS Solid Tumor Panel Panel
United States.
By Integrated Molecular Diagnostics Pathology, Inc. 152 Integrated Advantage NGS Solid Tumor Panel that also includes the following genes: ROS1 RRM1 SLCO1B1 BRAF BRCA1 SLC29A1 BRCA2 SMO SPARC SRC
More info about this panel United States.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
Rotor Syndrome: gene sequencing panel Panel
Canada.
By CEN4GEN Institute for Genomics and Molecular Diagnostics Rotor Syndrome: gene sequencing panel that also includes the following genes: SLCO1B1 SLCO1B3
More info about this panel Canada.
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