SLITRK1 gene related symptoms and diseases

All the information presented here about the SLITRK1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Table of contents:

Main symptoms and clinical features
Other symptoms and clinical features
Related Diseases
Current trends
Suitable testing panels

Top 5 symptoms and clinical features associated to SLITRK1 gene

Symptoms // Phenotype	% Cases
Depressivity	Very Common - Between 80% and 100% cases
Obsessive-compulsive behavior	Very Common - Between 80% and 100% cases
Hair-pulling	Very Common - Between 80% and 100% cases
Tics	Uncommon - Between 30% and 50% cases
Incoordination	Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with SLITRK1 gene alterations may also develop some of the following symptoms and phenotypes:

Not very common - Between 30% and 50% cases
Self-injurious behavior
Impulsivity
Muscle fibrillation
Self-mutilation
Echolalia
Disinhibition
Dyslexia
Arnold-Chiari malformation

And 26 more phenotypes, you can get all of them using our tools for rare diseases.

Rare diseases associated to SLITRK1 gene

Here you will find a list of rare diseases related to the SLITRK1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.

TRICHOTILLOMANIA; TTM

Description

Trichotillomania (TTM) is a neuropsychiatric disorder characterized by chronic, repetitive, or compulsive hair pulling resulting in noticeable hair loss. The activity causes distress to the individual and often interferes with functioning. Affected individuals may develop physical complications and often have overlapping psychologic disorders, such as Tourette syndrome (GTS ) or obsessive-compulsive disorder (OCD ) (review by Novak et al., 2009).

Most common symptoms of TRICHOTILLOMANIA; TTM

Depressivity
Alopecia
Obsessive-compulsive behavior
Alopecia of scalp
Hair-pulling

More info about TRICHOTILLOMANIA; TTM

SOURCES: MESH OMIM

GILLES DE LA TOURETTE SYNDROME; GTS

Alternate names

GILLES DE LA TOURETTE SYNDROME; GTS Is also known as ts, tourette syndrome, tourette disorder

Description

Tourette syndrome is a neurobehavioral disorder manifest particularly by motor and vocal tics and associated with behavioral abnormalities. Tics are sudden, brief, intermittent, involuntary or semi-voluntary movements (motor tics) or sounds (phonic or vocal tics). They typically consist of simple, coordinated, repetitive movements, gestures, or utterances that mimic fragments of normal behavior. Motor tics may range from simple blinking, nose twitching, and head jerking to more complex throwing, hitting, or making rude gestures. Phonic tics include sniffling, throat clearing, blowing, coughing, echolalia, or coprolalia. Males are affected about 3 times more often than females, and onset usually occurs between 3 and 8 years of age. By age 18 years, more than half of affected individuals are free of tics, but they may persist into adulthood (review by Jankovic, 2001).