WISP3 gene related symptoms and diseases
All the information presented here about the WISP3 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,NCBIGENE,OMIM,HGNC.
Top 5 symptoms associated to WISP3 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Autosomal recessive inheritance | Very Common - Between 80% and 100% cases |
| Flattened epiphysis | Very Common - Between 80% and 100% cases |
| Metaphyseal widening | Very Common - Between 80% and 100% cases |
| Spondyloepiphyseal dysplasia | Very Common - Between 80% and 100% cases |
| Rheumatoid arthritis | Very Common - Between 80% and 100% cases |
Other less frequent symptoms
Patients with WISP3 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
ArthropathyNot very common - Between 30% and 50% cases
Joint swellingCommonly - More than 50% cases
Abnormality of the kneeNot very common - Between 30% and 50% cases
Juvenile rheumatoid arthritisCommonly - More than 50% cases
SynovitisNot very common - Between 30% and 50% cases
Coxa varaCommonly - More than 50% cases
Methylmalonic acidemiaNot very common - Between 30% and 50% cases
OsteochondromaAnd 29 more phenotypes.
Accelerate your rare disease diagnosis with us
Rare diseases associated to WISP3 gene
Here you will find a list of rare diseases related to the WISP3. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
ARTHROPATHY, PROGRESSIVE PSEUDORHEUMATOID, OF CHILDHOOD; PPAC
Alternate names
ARTHROPATHY, PROGRESSIVE PSEUDORHEUMATOID, OF CHILDHOOD; PPAC Is also known as progressive pseudorheumatoid arthropathy of childhood, spondyloepiphyseal dysplasia tarda with progressive arthropathy;sedt-pa, progressive pseudorheumatoid dysplasia;ppd;spondyloepiphyseal dysplasia tarda-progressive arthropathy syndrome
Description
Progressive pseudorheumatoid arthropathy (dysplasia) of childhood (PPAC; PPD) presents as spondyloepiphyseal dysplasia (SED) tarda with progressive arthropathy and is described as a specific autosomal recessive subtype of SED.
Most common symptoms of ARTHROPATHY, PROGRESSIVE PSEUDORHEUMATOID, OF CHILDHOOD; PPAC
- Autosomal recessive inheritance
- Short stature
- Scoliosis
- Muscle weakness
- Pain
More info about ARTHROPATHY, PROGRESSIVE PSEUDORHEUMATOID, OF CHILDHOOD; PPAC
Potential gene panels for WISP3 gene
WISP3 - Progressive pseudorheumatoid dysplasia (PPRD) Panel
By Centre of Molecular Diseases (CMM) CHUV in Switzerland.
This panel specifically test the WISP3 gene.
More info about this panelWISP3. Complete sequencing Panel
By Instituto de Medicina Genomica Instituto de Medicina Genomica in Spain.
This panel specifically test the WISP3 gene.
More info about this panelArthropathy, progressive pseudorheumatoid of childhood (sequence analysis of WISP3 gene) Panel
By CGC Genetics in Portugal.
This panel specifically test the WISP3 gene.
More info about this panelSkeletal Disorders and Joint Problems Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics in United States. Skeletal Disorders and Joint Problems Sequencing Panel with CNV Detection that also includes the following genes: RECQL4 ALPL ANKH TYROBP FKBP10 B4GALT7 IFITM5 LRP5 COL2A1 COL1A1
More info about this panelSpondylo-Epi-Metaphyseal dysplasias Deletion / Duplication panel Panel
By Connective Tissue Gene Tests in United States. Spondylo-Epi-Metaphyseal dysplasias Deletion / Duplication panel that also includes the following genes: COL2A1 FGFR3 COL10A1 IDUA RMRP RUNX2 SBDS SLC26A2 TRPV4 HSPG2
More info about this panelSpondylo-Epi-Metaphyseal dysplasias Comprehensive panel Panel
By Connective Tissue Gene Tests in United States. Spondylo-Epi-Metaphyseal dysplasias Comprehensive panel that also includes the following genes: COL2A1 FGFR3 COL10A1 IDUA RMRP RUNX2 SBDS SLC26A2 TRPV4 HSPG2
More info about this panelSpondylo-Epi-Metaphyseal dysplasias NGS panel Panel
By Connective Tissue Gene Tests in United States. Spondylo-Epi-Metaphyseal dysplasias NGS panel that also includes the following genes: COL2A1 FGFR3 COL10A1 IDUA RMRP RUNX2 SBDS SLC26A2 TRPV4 HSPG2
More info about this panelProgressive pseudorheumatoid arthropathy of childhood Deletion / Duplication test Panel
By Connective Tissue Gene Tests in United States.
This panel specifically test the WISP3 gene.
More info about this panelProgressive pseudorheumatoid arthropathy of childhood Sequencing test Panel
By Connective Tissue Gene Tests in United States.
This panel specifically test the WISP3 gene.
More info about this panelProgressive pseudorheumatoid arthropathy of childhood Comprehensive test Panel
By Connective Tissue Gene Tests in United States.
This panel specifically test the WISP3 gene.
More info about this panelArthropathy, progressive pseudorheumatoid, of childhood Panel
By Centogene AG - the Rare Disease Company in Germany.
This panel specifically test the WISP3 gene.
More info about this panelSingle gene testing WISP3 Panel
By CeGaT GmbH in Germany.
This panel specifically test the WISP3 gene.
More info about this panelSpondylometaphyseal dysplasia and Spondylo-epi-(meta)-physeal dysplasia Panel Panel
By CeGaT GmbH in Germany. Spondylometaphyseal dysplasia and Spondylo-epi-(meta)-physeal dysplasia Panel that also includes the following genes: COL2A1 SLC39A13 RMRP TRPV4 HSPG2 COL11A1 COL11A2 CANT1 DYM B3GALT6
More info about this panelProgressive pseudorheumatoid arthropathy of childhood Panel
By Praxis fuer Humangenetik Wien in Austria.
This panel specifically test the WISP3 gene.
More info about this panelProgressive pseudorheumatoid arthropathy of childhood Panel
By MedGene in Slovakia.
This panel specifically test the WISP3 gene.
More info about this panelArthropathy, progressive pseudorheumatoid, of childhood: WISP3 gene sequence analysis Panel
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases in Spain.
This panel specifically test the WISP3 gene.
More info about this panelSkeletal dysplasias Panel
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases in Spain. Skeletal dysplasias that also includes the following genes: ALPL COL2A1 COL1A1 COL1A2 FGFR3 COL10A1 RMRP SBDS PEX7 SLC26A2
More info about this panelSkeletal Dysplasia: Sequencing Panel Panel
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics in United States. Skeletal Dysplasia: Sequencing Panel that also includes the following genes: RECQL4 ALPL ANKH TYROBP FKBP10 B4GALT7 IFITM5 LRP5 COL2A1 COL1A1
More info about this panelPan-Ethnic Carrier Screen: Gene Sequencing Panel Panel
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics in United States. Pan-Ethnic Carrier Screen: Gene Sequencing Panel that also includes the following genes: FMR1 HFE ACADM ACADS AGL ACADVL ACAT1 ALDOB ALPL BTD
More info about this panelSkeletal Dysplasias NGS panel Panel
By Fulgent Genetics Fulgent Genetics in United States. Skeletal Dysplasias NGS panel that also includes the following genes: RECQL4 ALPL ANKH TYROBP FKBP10 B4GALT7 IFITM5 LRP5 COL2A1 COL1A1
More info about this panelWISP3 Panel
By Fulgent Genetics Fulgent Genetics in United States.
This panel specifically test the WISP3 gene.
More info about this panelSpondylometaphyseal / Spondyloepi-(meta)-physeal Dysplasia Panel Panel
By Blueprint Genetics in Finland. Spondylometaphyseal / Spondyloepi-(meta)-physeal Dysplasia Panel that also includes the following genes: COL2A1 SLC39A13 RMRP TRPV4 HSPG2 COL11A1 COL11A2 CANT1 DYM BGN
More info about this panelSkeletal Dysplasias Core Panel Panel
By Blueprint Genetics in Finland. Skeletal Dysplasias Core Panel that also includes the following genes: ALPL ANKH FKBP10 LRP5 COL2A1 COL1A1 COL1A2 TGFB1 TNFRSF11A CLCN7
More info about this panelComprehensive Skeletal Dysplasias and Disorders Panel Panel
By Blueprint Genetics in Finland. Comprehensive Skeletal Dysplasias and Disorders Panel that also includes the following genes: RECQL4 ALPL ANKH TYROBP FKBP10 B4GALT7 LRP5 COL2A1 COL1A1 COL1A2
More info about this panelComprehensive Growth Disorders / Skeletal Dysplasias and Disorders Panel Panel
By Blueprint Genetics in Finland. Comprehensive Growth Disorders / Skeletal Dysplasias and Disorders Panel that also includes the following genes: RECQL4 ALPL ANKH TYROBP FKBP10 B4GALT7 BCS1L IFITM5 LRP5 COL2A1
More info about this panelProgressive pseudorheumatoid arthropathy of childhood Panel
By Bioarray in Spain.
This panel specifically test the WISP3 gene.
More info about this panelFoundationOne® Heme Panel
By Foundation Medicine, Inc. in United States. FoundationOne® Heme that also includes the following genes: BRCA1 BRCA2 VHL APC MSH2 MSH6 MLH1 MUTYH PTEN RUNX1
More info about this panelNeoTYPE® Discovery Profile for Solid Tumors Panel
By NeoGenomics Laboratories NeoGenomics Laboratories, Inc. in United States. NeoTYPE® Discovery Profile for Solid Tumors that also includes the following genes: BRCA1 BRCA2 VHL APC MSH2 PMS2 MSH6 MLH1 MUTYH PTEN
More info about this panelCaris MI TumorSeek 592-Gene NGS Panel Panel
By Caris Life Sciences in United States. Caris MI TumorSeek 592-Gene NGS Panel that also includes the following genes: BRCA1 BRCA2 VHL APC MSH2 PMS2 MSH6 MLH1 MUTYH PTEN
More info about this panelProgressive Pseudorheumatoid Arthropathy of Childhood, Sequencing WISP3 Gene Panel
By Reference Laboratory Genetics in Spain.
This panel specifically test the WISP3 gene.
More info about this panelRheumatoid Type Osteoarthropathy and Related Disorders , Panel Massive Sequencing (NGS) 7 Genes Panel
By Reference Laboratory Genetics in Spain. Rheumatoid Type Osteoarthropathy and Related Disorders , Panel Massive Sequencing (NGS) 7 Genes that also includes the following genes: COL2A1 TRPV4 LPIN2 WISP3 IL1RN HPGD ACAN
More info about this panelSkeletal Dysplasias , Panel Massive Sequencing (NGS) 36 Genes Panel
By Reference Laboratory Genetics in Spain. Skeletal Dysplasias , Panel Massive Sequencing (NGS) 36 Genes that also includes the following genes: ALPL COL2A1 COL1A1 COL1A2 FGFR3 COL10A1 RMRP SBDS PEX7 SLC26A2
More info about this panelPan-Ethnic Carrier Screen: Full Gene Sequencing and SMA Analysis Panel
By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada. Pan-Ethnic Carrier Screen: Full Gene Sequencing and SMA Analysis that also includes the following genes: HFE ACADM ACADS AGL ACADVL ACAT1 ALDOB ALPL BTD ATP7B
More info about this panelProgressive Pseudorheumatoid Dysplasia: gene sequencing Panel
By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.
This panel specifically test the WISP3 gene.
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like SGCE PHYKPL