CD28 gene related symptoms and diseases
All the information presented here about the CD28 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,ORPHANET,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to CD28 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Hepatomegaly | Very Common - Between 80% and 100% cases |
| Irregular hyperpigmentation | Very Common - Between 80% and 100% cases |
| Edema | Very Common - Between 80% and 100% cases |
| Neoplasm of the skin | Very Common - Between 80% and 100% cases |
| T-cell lymphoma | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with CD28 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Abnormal lymphocyte morphology
- Lymphoma
- Lymphadenopathy
- Dry skin
- Hypotrichosis
- Pruritus
- Skin rash
- Cutaneous T-cell lymphoma
And 32 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to CD28 gene
Here you will find a list of rare diseases related to the CD28. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
CLASSIC MYCOSIS FUNGOIDES
Alternate names
CLASSIC MYCOSIS FUNGOIDES Is also known as mycosis fungoides, alibert-bazin type
Description
Classical mycosis fungoides is the most common type of mycosis fungoides (MF; see this term), a form of cutaneous T-cell lymphoma, and is characterized by slow progression from patches to more infiltrated plaques and eventually to tumors.
Most common symptoms of CLASSIC MYCOSIS FUNGOIDES
- Hepatomegaly
- Edema
- Splenomegaly
- Alopecia
- Hyperkeratosis
More info about CLASSIC MYCOSIS FUNGOIDES
SÉZARY SYNDROME
Alternate names
SÉZARY SYNDROME Is also known as sÉzary lymphoma
Description
Sézary syndrome (SS) is an aggressive form of cutaneous T-cell lymphoma characterized by a triad of erythroderma, lymphadenopathy and circulating atypical lymphocytes (Sézary cells).
Most common symptoms of SÉZARY SYNDROME
- Neoplasm
- Abnormal facial shape
- Peripheral neuropathy
- Hepatomegaly
- Fever
More info about SÉZARY SYNDROME
Search interest in CD28
Potential gene panels for CD28 gene
CD28 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the CD28 gene.
More info about this panel United States.
Immune Report Card Panel
United States.
By OmniSeq, Inc. Immune Report Card that also includes the following genes: CXCL10 STAT1 TBX21 TGFB1 TNF TNFRSF14 TNFRSF18 CD40 CD27 TNFRSF9
More info about this panel United States.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
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