FOXC2 gene related symptoms and diseases
All the information presented here about the FOXC2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,ORPHANET,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to FOXC2 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Arrhythmia | Very Common - Between 80% and 100% cases |
| Muscle weakness | Very Common - Between 80% and 100% cases |
| Abnormality of cardiovascular system morphology | Very Common - Between 80% and 100% cases |
| Patent ductus arteriosus | Very Common - Between 80% and 100% cases |
| Hypogonadism | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with FOXC2 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Bruising susceptibility
- Cleft upper lip
- Paresthesia
- Abnormality of the liver
- Proteinuria
- Anxiety
- Photophobia
- Diabetes mellitus
And 78 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to FOXC2 gene
Here you will find a list of rare diseases related to the FOXC2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
TETRALOGY OF FALLOT
Description
Tetralogy of Fallot is a congenital cardiac malformation that consists of an interventricular communication, also known as a ventricular septal defect, obstruction of the right ventricular outflow tract, override of the ventricular septum by the aortic root, and right ventricular hypertrophy.
Most common symptoms of TETRALOGY OF FALLOT
- Growth delay
- Muscle weakness
- Cryptorchidism
- Anemia
- Brachydactyly
More info about TETRALOGY OF FALLOT
LYMPHEDEMA-DISTICHIASIS SYNDROME
Alternate names
LYMPHEDEMA-DISTICHIASIS SYNDROME Is also known as lymphedema with distichiasis
Description
Lymphedema - distichiasis is a rare syndromic lymphedema disorder characterized by lower-limb lymphedema and varying degrees of abnormal growth of eyelashes from the orifices of the Meibomian glands (distichiasis), with occasional associated manifestations.
Most common symptoms of LYMPHEDEMA-DISTICHIASIS SYNDROME
- Muscle weakness
- Cleft palate
- Pain
- Cataract
- Ptosis
More info about LYMPHEDEMA-DISTICHIASIS SYNDROME
Search interest in FOXC2
Potential gene panels for FOXC2 gene
Non-immune Hydrops Panel Panel
United States.
By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center Non-immune Hydrops Panel that also includes the following genes: RIT1 RPL11 RPL35A RPL5 RPS10 RPS17 RPS19 RPS24 RPS26 SEC23B
More info about this panel United States.
NGS Vascular Disorders Panel Panel
United States.
By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center NGS Vascular Disorders Panel that also includes the following genes: SOX18 TEK VEGFC GLMN KRIT1 STAMBP GJC2 ACVRL1 CCM2 CCBE1
More info about this panel United States.
Lymphedema NGS Multi-Gene Panel (36 Genes) Panel
Netherlands.
By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam Lymphedema NGS Multi-Gene Panel (36 Genes) that also includes the following genes: BRAF SOS1 SOX18 VEGFC CBL SHOC2 GJC2 TUBGCP6 CDK19 SPRED1
More info about this panel Netherlands.
FOXC2. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the FOXC2 gene.
More info about this panel Spain.
Lymphedema-distichiasis syndrome (sequence analysis of FOXC2 gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the FOXC2 gene.
More info about this panel Portugal.
Alveolar capillary dysplasia with misalignment of pulmonary veins (deletions/duplications analysis of 16q24.1 region) Panel
Portugal.
By CGC Genetics Alveolar capillary dysplasia with misalignment of pulmonary veins (deletions/duplications analysis of 16q24.1 region) that also includes the following genes: FOXC2 FOXF1 MYCN
More info about this panel Portugal.
Alveolar capillary dysplasia with misalignment of pulmonary veins (deletions/duplications analysis of 16q24.1 region) Panel
Portugal.
By CGC Genetics Alveolar capillary dysplasia with misalignment of pulmonary veins (deletions/duplications analysis of 16q24.1 region) that also includes the following genes: FOXC2 FOXF1 MYCN
More info about this panel Portugal.
Lymphedema Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Lymphedema Sequencing Panel with CNV Detection that also includes the following genes: SOX18 VEGFC GJC2 FAT4 PIEZO1 CCBE1 FLT4 FOXC2 GATA2 GJA1
More info about this panel United States.
Lymphedema-Distichiasis Syndrome via FOXC2 Gene Sequencing with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics
This panel specifically test the FOXC2 gene.
More info about this panel United States.
Lymphedema-distichiasis syndrome Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the FOXC2 gene.
More info about this panel Germany.
Vascular and lymphatic disorders Panel Panel
Germany.
By CeGaT GmbH Vascular and lymphatic disorders Panel that also includes the following genes: SOX18 TREX1 SERPING1 VEGFC KRIT1 GJC2 ACVRL1 CCM2 FAT4 CCBE1
More info about this panel Germany.
Developmental Eye Disease panel Panel
United States.
By Molecular Vision Laboratory Developmental Eye Disease panel that also includes the following genes: BMP4 SHH SIX3 SIX6 SLC25A1 SNX3 SOX2 SOX3 ELP4 VAX1
More info about this panel United States.
Primary lymphedema and Hydrops fetalis Panel
Belgium.
By Center for Human Genetics Cliniques Universitaires Saint Luc Primary lymphedema and Hydrops fetalis that also includes the following genes: SOS1 SOX18 VEGFC GJC2 FAT4 PIEZO1 CCBE1 EPHB4 FLT4 FOXC2
More info about this panel Belgium.
Lymphedema-distichiasis syndrome: FOXC2 gene sequence analysis Panel
Spain.
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases
This panel specifically test the FOXC2 gene.
More info about this panel Spain.
LYMPHEDEMA Panel
Spain.
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases LYMPHEDEMA that also includes the following genes: SOX18 ZMPSTE24 GJC2 CCBE1 FLT4 FOXC2 GATA2 KIF11 LMNA
More info about this panel Spain.
FOXC2 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the FOXC2 gene.
More info about this panel United States.
Renal Malformation Panel Panel
Finland.
By Blueprint Genetics Renal Malformation Panel that also includes the following genes: ROBO2 SALL1 BMP4 SIX1 SIX5 HNF1B WT1 ACTG2 FREM1 FREM2
More info about this panel Finland.
Lymphatic Malformations and Related Disorders Panel Panel
Finland.
By Blueprint Genetics Lymphatic Malformations and Related Disorders Panel that also includes the following genes: SOX18 GJC2 FAT4 PIEZO1 CCBE1 FLT4 FOXC2 GATA2 KIF11 PIK3CA
More info about this panel Finland.
Lymphedema - distichiasis Panel
Spain.
By Bioarray
This panel specifically test the FOXC2 gene.
More info about this panel Spain.
LYMPHEDEMA-DISTICHIASIS SYNDROME Panel
Spain.
By Laboratorio de Genetica Clinica SL
This panel specifically test the FOXC2 gene.
More info about this panel Spain.
Lymphedema-Distichiasis Syndrome , Sequencing FOXC2 Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the FOXC2 gene.
More info about this panel Spain.
Lymphedema-Lethal Restrictive Dermopathy , Panel Massive Sequencing (NGS) 7 Genes Panel
Spain.
By Reference Laboratory Genetics Lymphedema-Lethal Restrictive Dermopathy , Panel Massive Sequencing (NGS) 7 Genes that also includes the following genes: SOX18 VEGFC ZMPSTE24 FLT4 FOXC2 GATA2 KIF11
More info about this panel Spain.
Lymphedema-Distichiasis Syndrome: gene sequencing Panel
Canada.
By CEN4GEN Institute for Genomics and Molecular Diagnostics
This panel specifically test the FOXC2 gene.
More info about this panel Canada.
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