Parkinson Disease 8, Autosomal Dominant; Park8

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Genes related to Parkinson Disease 8, Autosomal Dominant; Park8

LRRK2

View recommended genes panels

Clinical Features

Top most frequent phenotypes and symptoms related to Parkinson Disease 8, Autosomal Dominant; Park8

Seizures
Cognitive impairment
Delayed speech and language development
Tremor
Dementia
Cerebral cortical atrophy
Rigidity
Mental deterioration
Postural instability
Parkinsonism

And another 21 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Parkinson Disease 8, Autosomal Dominant; Park8 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
LRRK2 DNA Sequencing Test. By Athena Diagnostics Inc (United States). LRRK2 Specificity 100 % Genes 100 %
Complete Parkinsonism Evaluation. By Athena Diagnostics Inc (United States). SNCA, PINK1, PARK7, LRRK2, PRKN Specificity 20 % Genes 100 %
LRRK2 DNA Test. By Athena Diagnostics Inc (United States). LRRK2 Specificity 100 % Genes 100 %
Movement Disorders Panel. By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States). SCP2, SGCE, SLC20A2, SLC2A1, SLC6A3, SNCA, SPR, SQSTM1, SUCLA2, SUOX, TAF1, TH, TIMM8A, TREX1, MCOLN1, VPS35, FBXO7, CACNA1A, NPC2, PINK1 , (...) View the complete list with 72 more genes Panel complete gene list SCP2, SGCE, SLC20A2, SLC2A1, SLC6A3, SNCA, SPR, SQSTM1, SUCLA2, SUOX, TAF1, TH, TIMM8A, TREX1, MCOLN1, VPS35, FBXO7, CACNA1A, NPC2, PINK1, PANK2, SAMHD1, APTX, SLC19A3, PARK7, TRIM32, TPK1, TREM2, ARX, RNASEH2A, LRRK2, VPS13A, L2HGDH, THAP1, FA2H, PDHX, ADAR, CP, RNASEH2C, CSF1R, CHMP2B, MMADHC, C19orf12, RNASEH2B, DCAF17, CYP27A1, FOXRED1, DCTN1, DDC, WDR45, DLAT, FASTKD2, EARS2, ATP13A2, DRD2, DRD5, PRRT2, SLC46A1, TOR1A, AFG3L2, SDHAF1, ERCC6, FOXG1, FTL, FUCA1, GAMT, GBA, GCDH, GCH1, MR1, HPRT1, AP1S2, KCNQ2, MAPT, MAT1A, ARSA, MPV17, ATM, ATP1A2, ATP1A3, PRKN, ATP7B, KIF1A, AUH, PLA2G6, PLP1, PNKD, POLG, PSEN1, PTEN, PTS, QDPR Specificity 2 % Genes 100 %
Parkinson's Disease. By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States). SLC6A3, SNCA, TAF1, TH, VPS35, FBXO7, PINK1, PARK7, LRRK2, CSF1R, DCTN1, ATP13A2, GBA, GCH1, MAPT, ATP1A3, PRKN, PLA2G6, POLG Specificity 6 % Genes 100 %
LRRK2. By Institute for Human Genetics University Clinic Freiburg (Germany). LRRK2 Specificity 100 % Genes 100 %
Detection of the G2019S mutation in exon 41 of the LRRK2 gene. By Neurogenetics Department Cyprus Institute of Neurology and Genetics (Cyprus). LRRK2 Specificity 100 % Genes 100 %
LRRK2. Sequencing of the exons 31, 35 and 41. By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain). LRRK2 Specificity 100 % Genes 100 %

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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Symptoms Checker

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